Research Associate in Chemical Proteomics
Posted on March 23, 2026 (2 months ago)
This job post is archived - the company is no longer hiring for this position.
Check out other job posts of this company here!Research Associate in Chemical Proteomics
The Rosalind Franklin Institute (the Franklin) is a technology institute established by the UK Government as a unique centre committed to advancing tools that are needed to transform healthcare in the future.
The Institute brings together researchers in life and physical sciences, and engineering, to develop a spectrum of tools which we will use to image, interpret and intervene in biological systems. These insights will speed up the discovery of new medicines, help find new diagnostics and contribute to a deeper understanding of human health and disease. Our Science Strategy seeks to focus the Franklin’s research and unite our researchers around our Technology Innovation Challenges and Life Science Challenges.
As a Research Associate in Chemical Proteomics at the Franklin, you will bring scientific knowledge and skills to deliver a specific research project and/or you will bring independent, creative science, or specific skills to a team delivering a project or program. Through this work, you will build scientific independence, develop new science and leadership skills, and establish a growing reputation externally.
In particular, you will be responsible for developing new MS methodologies to investigate complex proteomes with high sensitivity and precision. You will work alongside researchers to apply these methods to answer questions across complex biological samples (e.g. cells, organoid, tissue). Whilst this position is primarily research focussed, you will also work closely with the Franklin proteomics core facility to help maintain equipment, reagents, potential sample sources, and help demonstrate newly developed technologies.
Key Responsibilities
- Carry out analytical procedures for proteome characterisation to a high degree of precision, including sample preparation.
- Analyse and interpret quantitative proteomic data with statistical rigour using common freely available software packages.
- Help to devise then create proteomic methodologies (sample preparation, liquid chromatography (LC) and mass spectrometry) to address specific biological questions.
- Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques.
- Assist with general laboratory maintenance including troubleshooting and upkeep of nanoLCs, centrifugal evaporators, liquid handlers, and various MS equipment.
- Help devise methods for supporting diverse sample sources including cell lines, cell samples, tissue samples and organoids.
- Work alongside the proteomics facility to ensure upkeep of nanoLCs, centrifugal evaporators, liquid handlers and other MS equipment.
- Liaise with laboratory support and service staff, engineers, and scheduling servicing for day-to-day maintenance and minor servicing.
- Enhance research through collaboration and exchange of ideas within your network.
- Work within larger project teams contributing to Institute-wide projects around key Franklin Challenges.
- Ensure efficient methods across the Franklin and Harwell environment.
- Publish research articles in leading academic journals and present findings at national and international meetings/conferences.
- Support and develop others including day-to-day supervision of students or visitors related to your research.
- Participate in and support public engagement and widening access activities of the Franklin.
- Carry out other duties reasonably requested for the normal running of the facility.
Person Specification and Additional Information
The job requires candidates to hold a PhD/DPhil (or equivalent); candidates who have submitted their PhD/DPhil thesis may be considered, in which case the initial appointment will be made at £37,500 per annum (to be increased on completion of the PhD/DPhil qualification).
The Franklin is committed to equality, diversity and inclusion and encourages applications from a diverse range of candidates. Adjustments can be made for candidates with specific needs by contacting [email protected] confidentially.
Benefits
- 25 days holidays plus bank holidays and Christmas holiday shutdown
- Generous pension scheme (employer’s contribution currently up to 18%)
- Group Life Assurance (Death in Service)
- Buying and Selling Annual Leave
- Workplace Nursery Salary Sacrifice Scheme
- Hub building with state-of-the-art laboratories
- Hybrid and flexible working
- Training and development opportunities
- Bus pass discount scheme and good transport links to Oxford and surrounding areas
- Cycle to Work Scheme
- Access to employee discount platform (Perkbox)
- Occupational Health and wellbeing support including Employee Assistance (24/7)
- Health Cash Plan
- Subsidised canteen and food outlets on campus
- Free on-site parking
- Campus location in beautiful countryside with social and sports clubs open to staff
How to Apply
To be considered for this role, please submit a CV and a cover letter explaining why you are the right person for this job. Please include information about your education and work experience.
Applicants should read the Job Information Pack for full details of the role (see Documents/Job Pack on the vacancy page).
Important Dates and Contact
Closing date for applications: 23:59 on Sunday 29th March 2026.
For adjustments or to discuss specific needs confidentially please contact [email protected].
Applicants should refer to the Candidate Privacy Policy on the Rosalind Franklin Institute website.