Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to accelerating patient access to evidence-based innovation in mental health. The company is headquartered in London, UK, with offices in New York City, USA. They focus on developing novel treatments with the potential to improve lives of those suffering from mental health conditions not helped by current treatments.

They are pioneering a new paradigm for treating mental health conditions with their investigational COMP360 synthetic psilocybin treatment, granted Breakthrough Therapy designation by the US FDA and Innovative Licensing and Access Pathway designation in the UK for treatment-resistant depression (TRD). Currently, they are in phase 3 for TRD, have completed phase 2 studies for PTSD and anorexia nervosa, and plan further late-stage study in PTSD.

The Senior Statistical Programmer will contribute expert programming skills to deliver accurate, regulatory-compliant clinical data outputs for development programs. The role requires technical proficiency, collaboration, and adaptability to support complex clinical trials.

Location: East Coast, USA or hybrid in NYC office.

Reports to: Associate Director, Statistics and Data Management.

Type: Fixed-term contract for 9 months.

Leading and coordinating programming activities within agreed timelines; managing internal and external study reporting; programming outputs per analysis plan; collaborating closely with study statisticians; reviewing Statistical Analysis Plans and shells; creating and reviewing SDTM and ADaM study specifications; ensuring programs, datasets, and outputs are appropriate for regulatory submission; performing simulations and data modeling; performing interim analyses; liaising with external vendors on deliverables.

Extensive experience in statistical programming; expertise in CDISC; proficient in SAS programming, statistical analyses, and macro creation, preferably also R; experience across all clinical development phases including efficacy, safety, PK, ISS/ISE reporting; quality control checks; knowledge of regulatory submission processes; understanding of ICH guidelines and regulations such as 21 CFR Part 11; experience supporting NDA submissions (FDA, EMA, MHRA) and addressing regulatory queries; problem-solving skills and risk mitigation recommendations; strong written and verbal communication skills; teamwork skills including cross-functional collaboration within the Statistics and Data Management Team.

For benefits and compensation overview, see the Working at Compass page on the company's website.

Committed to workplace wellbeing and reasonable accommodation during the interview process. Committed to diversity and equality under the Equality Act 2010 and equal opportunity employment in the US. No discrimination based on protected characteristics.

Employment visa sponsorship is not available. Only applications from those with employment rights in the applying country are accepted.

All data is confidential and protected by legal and data privacy requirements as explained in the company's recruitment Privacy Notice.