Scientific Program Manager
Posted on November 10, 2025 (about 2 hours ago)
About Chai Discovery
Chai Discovery is re-architecting drug discovery by building frontier AI foundation models to design molecules, and turning them into products that can transform how medicines are made.
The Chai founding team brought together leading researchers in this space and top operators in silicon valley. Our founders led seminal accomplishments at top AI-for-biology programs and labs, co-invented protein language modelling, built state-of-the-art folding algorithms, and sold AI adopted by top-10 pharma companies. We are backed by top-tier investors, including OpenAI, Thrive Capital, Dimension, Conviction, Lachy Groom, Amplify, and many more.
About the role
We are looking for a scientist with project management chops to oversee our lab experimentation and data generation efforts. Experimental data is key to testing research hypotheses and training frontier AI models. You will set and implement the vision for scaling Chai92s lab-in-the-loop data engine, managing CRO partners, and working hand-in-hand with our science and AI research teams.
This is a chance to push the boundaries of drug discovery and contribute to some of most advanced AI models ever built. Immerse yourself in technologies that represent the future of biotech, and position yourself at the forefront of this emerging field. Join a craft-obsessed team setting out to rewrite science & save lives.
About you
Our ideal candidate has a strong biologics and therapeutics background. You operate with urgency and are an outstanding scientific communicator. You have extensive experience working with CROs.
You have a deep desire to push the limits of what92s possible in therapeutic design and a restless drive to solve real-world problems and iterate quickly. Exposure to startups or other intense environments is important.
Scientific Background
- PhD or equivalent work experience in Biological Sciences, Protein Engineering, Biochemistry, or a related field
- Expertise with design and characterization of traditional and next-generation biologics, spanning monoclonals, bispecifics, TCEs, engineered cytokines, multifunctionals, and ADC/DAC formats
- Familiar with a broad array of design constructs, expression and purification campaigns, and fit-for-purpose binding and developability assays (SPR/BLI, ELISA, flow cytometry, etc.
- Able to expertly inspect data, draw sound conclusions, and summarize key findings
- Understand molecular-biology workflows for cloning, transient/stable expression, purification, and quality control
- Literate with computational biology tools like GraphPad Prism, Python, and R
Execution & Collaboration:
- Proven record of designing experimental plans and managing CRO relationships from SOW through data review
- Able to juggle multiple projects, adapt priorities quickly, and communicate results to colleagues in a tight feedback loop
- Excellent at communicating with internal & external audiences, from research associates to executives
Mindset
- Organized and scrappy
- Detail-oriented and fast-moving
- Flexible
- Proactive
- Ambitious
We offer
- Frontier technology: we92re developing the next frontier of AI-driven drug discovery that will fundamentally change how new therapeutics are created.
- World-class team: opportunity to work with world-renowned leaders in the AI x biology and technology ecosystem who have created some of the most impactful advancements.
- Highly competitive compensation: we offer highly competitive salary, equity package, and healthcare and wellness benefits.
- Velocity and ownership: we move incredibly fast, which means continuous learning and career growth opportunities are a guarantee. Every team member owns a significant slice of the roadmap.
- Strong team culture: Collaborative and supportive startup culture in a small and high-energy team who are guided by our mission to increase the efficiency of creating new medicines and positively impact millions of lives.
How to Apply
Please visit our job application page to apply for this position: Apply for this Job