32 Biosciences was born out of a groundbreaking vision to redefine healthcare through the power of the gut microbiome. Rooted in over two decades of pioneering research at The University of Chicago and the University of Wisconsin-Madison, the company was founded by three world-renowned scientists—Dr. John Alverdy, Dr. Gene Chang, and Dr. Joseph Pierre. Their insights into the gut microbial organ revealed its pivotal role in human health, inspiring innovative solutions to address unmet medical needs. The name “Three Squared Biosciences” reflects the exponential impact of the founders’ collaboration and their commitment to advancing microbiome science. Today, 32 Biosciences is at the forefront of microbiome-based diagnostics and interventions, translating cutting-edge research into transformative healthcare solutions.

Our vision is to establish the gut microbiome as the sixth vital organ, recognized globally as a cornerstone of human health, and to lead the microbiome sector with cutting-edge diagnostic tools and microbiome-based interventions.
Our mission is to revolutionize healthcare by defining, diagnosing, and restoring the functional health of the gut microbiome to prevent and treat chronic diseases, thereby improving health span and longevity.